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Relatively oliguric patientsespecially those with tubular necrosis in the immediate postcadaveric transplant periodmay have delayed clearance of IMURAN or its metabolitesmay be particularly sensitive to this drugand are usually given lower doses.

Patients receiving immunosuppressantsincluding Imuranare at increased risk for bacterialviralfungal,protozoaland opportunistic infectionsincluding reactivation of latent infectionsThese infections may lead to seriousincluding fatal outcomes.

Evidence indicates that Imuran therapy should be maintained indefinitelyeven if only low doses are necessarybecause of the risk of graft rejection.

If you have an allergy to azathioprine or any other part of Imuranazathioprine tabletsIf you are allergic to any drugs like this oneany other drugsfoodsor other substancesTell your doctor about the allergy and what signs you hadlike rashhivesitchingshortness of breathwheezingcoughswelling of facelipstongueor throator any other signsIf you have ever been treated with chlorambucilcyclosporineor melphalan in the pastIf you are breast-feeding or plan to breast-feed.

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